The web-based Enterprise Manager tool was introduced in Oracle 10g and has significant functionality improvements over previous versions. Even so, it seems there is not a day goes by without someone asking how to solve an Enterprise Manager configuration issue, so this article explains the first things you should look at. It's not meant to be an all encompassing guide. Just a first shot.
Make sure the "/etc/hosts" file contains at least the loopback address and preferably the machine definition also.
If you are using 11g, make sure the ORACLE_HOSTNAME and ORACLE_UNQNAME environment variables are set correctly.127.0.0.1 localhost.localdomain localhost 192.168.0.181 myserver.localdomain myserver
Check the listener is running correctly.ORACLE_HOSTNAME=myserver.localdomain; export ORACLE_HOSTNAME ORACLE_UNQNAME=DB11G; export ORACLE_UNQNAME
lsnrctl status